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中晚期中央型肺癌介入治疗的临床研究
引用本文:余昶,黄晓颖,王良兴,周为中,胡文豪. 中晚期中央型肺癌介入治疗的临床研究[J]. 中国医师进修杂志, 2007, 30(3)
作者姓名:余昶  黄晓颖  王良兴  周为中  胡文豪
作者单位:1. 325000,温州医学院附属第一医院介入放射科
2. 325000,温州医学院附属第一医院呼吸内科
基金项目:温州市科技局资助项目(Y2003A061)
摘    要:目的对比分析中晚期中央型肺癌支气管动脉介入治疗与全身静脉化疗的疗效。方法中央型中晚期肺癌85例,均经病理证实,分为支气管动脉介入治疗组与全身静脉化疗组。结果支气管动脉介入治疗组肺内原发病灶、远处转移灶、肺外淋巴结转移灶的有效率分别为59.52%、18.18%、55.56%;全身静脉化疗组分别为30.23%、53.85%、52.63%。肺内原发病灶、远处转移灶两组间有效率的差异有统计学意义(P<0.05)。结论支气管动脉介入治疗比全身静脉化疗能更有效地控制肺内原发病灶,但对远处转移灶治疗控制能力较低。

关 键 词:支气管肺癌  支气管动脉灌注  介入疗法  静脉化疗

Clinical study of interventional theraphy in moderate-late central type carcinoma of lung
YU Chang,HUANG Xiao-ying,WANG Liang-xing,ZHOU Wei-zhong,HU Wen-hao. Clinical study of interventional theraphy in moderate-late central type carcinoma of lung[J]. Chinese Journal of Postgraduates of Medicine, 2007, 30(3)
Authors:YU Chang  HUANG Xiao-ying  WANG Liang-xing  ZHOU Wei-zhong  HU Wen-hao
Abstract:Objective To compare the therapeutic effectiveness of bronchial arterial infusion(BAI) and traditional vein chemotherapy in moderate-late central type carcinoma of lung.Method Eighty-five patients with moderate-late central type carcinoma of lung were randomly treated by BAI(BAI group) and traditional vein chemotherapy(traditional vein chemotherapy group).Results The response rate of primary lesion,metastasis,transfer of lymph nodes in BAI group were 59.52%,18.18%,55.56%,in traditional vein chemotherapy group were 30.23%,53.85%,52.63%.The response rate of primary lesion,metastasis were different between the two groups(P <0.05).Conclusion BAI is better than traditional vien chemotherapy in effect of lung primary lesion,but is worse than traditional vein chemotherapy in effect of metastasis.
Keywords:Bronchopulmonarycarcinoma  Bronchoarterial infusion  Interventional therapy  Vein chemotherapy
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