老年人巨幼细胞性贫血临床分析

目的探讨老年人巨幼细胞性贫血（巨幼贫）的特点。方法对１９９５～１９９８年住院的１７例患者进行临床分析。结果全部患者均呈典型的巨幼贫骨髓象，血清叶酸或维生素Ｂ１２下降。病因方面７例有消化道疾患，其他方面为高血压，糖尿病，冠心病等。有１２例患者全血细胞下降。与非老年巨幼细胞贫血骨髓增生程度比较，呈增生下降，有明显差异。２例呈双相性贫血，即同时合并缺铁性贫血。结论当老年人以头昏、眼花、纳差等主诉就诊，而血常规呈大细胞、高色素贫血，要考虑巨幼贫的诊断，而一旦巨幼贫确诊，用叶酸、维生素Ｂ１２治疗效果非常显著。

Clinical analysis of megaloblastic anemia among old people

Objectives To explore the characteristics of megaloblastic anemia(MA) among old people. Methods Cinical analysis were made using the 17 cases of MA hospitalized in 19951998. ResultsAll cases had typical MA bone marrow and decline in serum folic acid or VitB12.Seven of the cases of MA had dyspepsia ,hypertension,diabetes,coronary heart disease. 12 cases showed a decline in blood cells . As compared with non old people MA bone marrow there was a decline in hyperplasia .2 cases had dimorphi anemia:that was they also suffer irondeficiency anemia. Conclusions When patients complained of dizziness,dim - sightedness,and routine blood tests showed macrocytic and hyerchromic anemia,MA should be considered.Once MA was diagnosed,the treatment with folic acid and VitB12 would be very effective.