胎龄≤34周的早产儿宫外发育迟缓发生情况及影响因素分析

目的 分析胎龄≤34周早产儿宫外发育迟缓(EUGR)发生率及其影响因素,为促进早产儿的生长发育提供参考.方法 回顾性分析2016年1月-2018年1月于南京市妇幼保健院分娩的315例胎龄≤34周早产儿临床资料,根据是否出现EUGR分为发育迟缓组与发育正常组,采用多因素Logistic回归分析早产儿宫外发育迟缓的影响因素...

Occurrence and influencing factors of extrauterine growth retardation in premature infants not older than 34 weeks old

Objective To explore the incidence and influencing factors of extrauterine growth retardation(EUGR) in premature infants with gestational age ≤ 34 weeks old, in order to provide reference for facilitating the healthy growth and development of preterm infants. Methods The clinical data of 315 premature infants whose gestational age was ≤ 34 weeks and were delivered in Nanjing Maternal and Child Health Hospital from January 2016 to January 2018 were retrospectively collected and analyzed.According to whether infants had EUGR or not, infants were divided into developmental retardation group(retardation group) and typical development group(normal group).The influencing factors of EUGR in preterm infants were analyzed by multivariate Logistic regression analysis. Results The proportions of birth weight ＜1 500 g, gestational age＜28 weeks, head circumference at birth ≤33 cm, duration of body mass decline ＞6 d, maternal gestational hypertension, minimum body weight and body mass at discharge indevelopmental retardation group were significantly higher than those in typical development group(P<0.05).And the first breastfeeding time, time for achieving enteral feeding, intravenous nutrition duration, duration of minimal feeding, the proportions of sepsis, respiratory distress syndrome and feeding intolerance were significantly higher than those in typical development group(P<0.05).Multivariate Logistic regression analysis showed that birth weight＜1 500 g(OR=1.719, 95%CI:1.115—2.652), gestational age ＜28 weeks(OR=1.587, 95%CI:1.052—2.396) and time for achieving enteral feeding≥17 d(OR=1.835, 95%CI:1.144—2.943) were risk factors of EUGR in premature infants(P<0.05). Conclusions The influencing factors of EUGR in premature infants with gestational age is ≤34 weeks include birth weight, gestational age and time for achieving enteral feeding.And nutritional support should be taken as soon as possible to reduce EUGR risk.