北京地区0~3月龄婴儿超重与骨密度的关系

目的 研究0~3月龄超重婴儿骨密度的情况,为婴儿期骨骼发育保健工作提供指导。方法 纳入2019年1月-2020年1月于北京积水潭医院体检的1 052名0~3月龄婴儿进行研究。由于男女身长、体重、骨骼超声信号声速值(SOS)评估标准不同,所以分别对不同性别研究对象进行研究,按照2006年WHO《儿童发育标准》分为超重组和正常组,比较两组间骨密度差异。并对组内不同性别骨密度进行比较。结果 男性、女性超重组及正常组组间SOS水平差异均无统计学意义(P>0.05);超重组内男女骨密度Z值水平及正常组内男女骨密度Z值水平差异亦均无统计学意义(t＝-1.23,-0.47,P>0.05)。结论 0~3月龄阶段,超重与骨密度尚未发现明显相关性,但尚缺少各种影响因素及年龄增长与骨密度之间关系的进一步研究,仍需更多的探索以对临床提供更好指导。

Relationship between overweight and bone mineral density in infants aged 0 to 3 months in Beijing

Objective To study the relationship between bone mineral density(BMD)and overweight infant of 0-3 months,so as to provide guidance for the health care of bone development in infancy.Methods Infants aged 0-3 months who took physical examination were investigated from January 2019 to January 2020.Because of the difference on the standards for body length,weight,speed of sound(SOS)between boys and girls,the research objectives of different genders were compared seperately.According to the 2006 WHO Child Growth Standards,research objectives were divided into overweight group and normal group.The level of BMD between overweight group and normal group was compared.Then,the BMD level was compared between different genders in each group.Results There were no significant differences on the level of SOS between overweight group and normal group in boys and girls(P>0.05).Z value did not showed significant differences between boys and girls in overweight group and normal group(t=-1.23,-0.47,P>0.05).Conclusions No significant correlation has been found between overweight and BMD in 0 to 3-month-old children.However,further studies are warranted to explore the relationship between various influencing factors and BMD or between aging and BMD,thereby providing better guidance for clinical practice.