父母超重肥胖与儿童代谢指标异常聚集性的关系

目的 探讨父母超重肥胖与儿童代谢指标异常聚集性的关系,为心血管病危险因素的防控提供科学依据。方法 2017年11月-2018年1月采用方便整群抽样的方法,以山东省淄博市桓台县某所小学作为调查点,将身体测量、问卷调查和血生化检测均完整的1 280名6~11岁儿童作为研究对象。分析父母超重肥胖与儿童代谢指标异常及其聚集性的关系。结果 父母一方和双方均超重肥胖的检出率分别为55.6%和19.8%。儿童代谢指标异常(腹型肥胖、血压偏高)及其聚集性(2项和≥3项代谢指标异常)检出率在父母不同体重状态组间差异有统计学意义(P<0.05或<0.001)。与父母均体重正常的儿童相比,父母一方超重肥胖儿童存在腹型肥胖(OR＝2.00)和1项代谢指标异常(OR＝1.47)的危险性较高(P<0.05或<0.001),而双方均超重肥胖儿童存在腹型肥胖(OR＝3.08)、血压偏高(OR＝1.74)和代谢异常指标聚集(OR＝1.64~4.60)的危险性更高(P<0.05或<0.001)。结论 父母超重肥胖与儿童腹型肥胖、血压偏高和代谢指标异常聚集性存在关联。这提示应该对有父母超重肥胖史的高危儿童进行重点干预。

Association between parental overweight or obesity and clustering of cardio-metabolic risk factors in children

Objective To examine the association between parental overweight or obesity and clustering of cardio-metabolic risk factors in children,so as to provide scientific evidence for prevention and control of cardiovascular risk factors.Methods A convenient cluster sampling method was used to conduct a cross-sectional study from a primary school in Huantai county,Zibo city,Shandong.A total of 1280 children aged 6-11 years with complete data on physical examinations,information from a questionnaire and blood biochemical variables were enrolled in this study.The correlation between parental overweight or obesity and clustering of cardio-metabolic risk factors in children was analyzed.Results The prevalence rates of overweight or obesity among either and both parents were 55.6%and 19.8%,respectively.The prevalence rates of abnormal metabolic indices(abdominal obesity and elevated blood pressure)and the clustering of abnormal metabolic indices were significantly different among parents with different weight status(P<0.05 or<0.001).Compared with children whose parents both had normal weight,those whose either mother or father was overweight or obese had higher risk for developing abdominal obesity(OR=2.00)and one abnormal metabolic indices(OR=1.47)(P<0.05 or<0.001).However,children whose parents both had overweight or obesity had much higher risk of developing abdominal obesity(OR=3.08),elevated blood pressure(OR=1.74)and abnormal metabolic indices(OR=1.64-4.60)(P<0.05 or<0.001).Conclusion Parental overweight or obesity is associated with abdominal obesity,elevated blood pressure and clustering of abnormal metabolic indices in children,suggesting high-risk children whose parents had history of overweight and obesity should be prioritized for giving intervention.