舒芬太尼静脉麻醉在神经外科手术中的应用

目的：比较芬太尼与舒芬太尼在神经外科手术中的麻醉效果。方法选取150例神经外科手术患者为研究对象，依据麻醉方式不同，随机分为观察组和对照组各75例。对照组采用芬太尼联合丙泊酚静脉麻醉，观察组采用舒芬太尼联合丙泊酚静脉麻醉。观察围术期两组患者麻醉中血流动力学变化及术后不良反应。结果观察组麻醉插管后5 min、拔管时HR、MAP波动、术后苏醒时间、术后呕吐、烦躁、呼吸抑制等不良反应发生率均明显低于对照组（ P＜0.05）。结论舒芬太尼麻醉对血氧代谢影响小，术后苏醒快，可作为神经外科麻醉的首选药物。

The Application of Sufentanil Intravenous Anesthesia in Operations of Patients in Department of Neurosurgery

Objective To compare the anesthesia effect of operations between fentanyl and sufentanil in patients in the Department of Neurosurgery.Methods 150 patients in Department of Neurosurgery, on the basis of different ways of anesthesia, were randomly divided into obser-vation group and control group with 75 cases in each group.The control group was treated with the intravenous anesthesia of fentanyl combined with propofol, but the observation group was treated with the sufentanil combined with propofol.The Hemodynamics changes and adverse reaction in the two groups were observed after anesthesia.Results The HR and MAP fluctuated in the observation group after anesthesia intubation and removing and the incidence rate of postoperative recovery time, postoperative vomiting, restlessness and respiratory depression were significantly lower than those in the control group （ P〈0.05） .Conclusion The sufentanil an-esthesia has little influence on the oxygen metabolism and faster postoperative recovery.It has been the first choice of drug in the Department of Neurosurgery anesthesia.