卡他莫拉氏菌下呼吸道感染58例报告

的 :总结近五年来卡他莫拉氏菌下呼吸道感染的临床特点及对抗生素的敏感性。方法 :(1 )分析 58例卡他莫拉氏菌所致肺部感染的临床资料 ,包括年龄、基础疾病、发病诱因、症状体征、X线表现、治疗转归等 ;(2 )以K -B法 (纸片法 )或Etest法 (MIC纸片法 )测定该菌的体外药敏性。结果 :(1 )男 44例 ,女 1 4例 ,年龄 54± 1 5岁 ,78%的患者有基础疾病 ,主要为COPD、肺心病。症状为咳嗽 (93 % )、发热 (60 % ) ,胸部X线表现为肺部斑片状阴影 (41 4% )。 (2 )药敏试验示该菌呈多重耐药 ,妥布霉素、氧氟沙星、头孢哌酮、头孢三嗪为较敏感抗生素。结论 :卡他莫拉氏菌下呼吸道感染患者多有基础疾病 ,临床表现不典型 ,诊断依靠病原学并结合临床及X线检查 ,治疗应根据药敏并联合应用抗生素

Lower respiratory tract infection by branhamella catarrhalis:A report of 58 cases

Objective:To study the clinical characteristics of lower respiratory tract infection caused by branhamella catarrhalis,and to investigate the drug sensitivities of branhamella catarrhalis strains.Methods:(1)Analysing the clinical data of 58 cases with lower respiratory tract infection of enterobacter cloacae defined by a putative standard,including ages,symptoms,signs,underlying diseases,sputum culture,X-ray findings and the prognosis.(2)Determining the drug sensitivities against the branhamella catarrhalis strains by K-B method.Results:(1)There were 44 males and 14 females,with the mean age 54.Fifteen cases diagnosed,who had underlying diseases,most were COPD.The chief symptoms were fever (60%) and productive cough (93%).The chest X-ray revealed inflammatory infiltration in lower lobes of both sides.(2)The antimicrobial tests in vitro showed that these strains were multiresistant to antibiotics,but tobramycin,cefoaperazone were sensitive.Conclusions:The lower respiratory tract infections caused by branhamella catarrhalis show no specific clinical manifestations.The diagnosis should be made according to bacteriologic examination combined with and X-ray manifestations.Combining antibiotics therapy is recommanded according to antimicrobial sensitivity test.