| 诱生型一氧化氮合酶在正常豚鼠耳蜗内的分布 |
| |
| 引用本文： | 沈静,汤浩,章晓芳. 诱生型一氧化氮合酶在正常豚鼠耳蜗内的分布[J]. 中国医科大学学报, 2000, 29(3): 180-181 |
| |
| 作者姓名： | 沈静 汤浩 章晓芳 |
| |
| 作者单位： | 中国医科大学基础医学院听力研究室!沈阳110001 |
| |
| 摘 要： | 目的：观察诱生型一氧化氮合酶（ｉｎｄｕｃｉｂｌｅ ｎｉｔｒｉｃ ｏｘｉｄｅ－ｓｙｎｔｈａｓｅ，ｉＮＯＳ）在正常豚鼠耳蜗内的分布，方法：以特异性ｉＮＯＳ抗体，应用免疫组化ＡＢＣ法结合显微图像定量分析技术，在１０只正常豚鼠耳蜗冰冻切片上检测ｉｎＯＳ。结果：ｉＮＯＳ的阳性免疫反应产物分布于耳蜗的血管纹、螺旋神经节细胞、Ｃｏｒｔｉ器的内、外毛细胞及神经纤维。结论：正常豚鼠耳蜗有ｉＮＯＳ表达，提示ｉＮＯＳ可
|
| 关 键 词： | 诱生型一氧化氮合酶 耳蜗 豚鼠 免疫组织化学 |
Distribution of Inducible Nitric Oxide Synthase in Cochlea of Normal Guinea Pigs |
| |
| Shen Jing,Tang Hao,Zhang Xiaofang,Zhang He,Zhang Tiemin. Distribution of Inducible Nitric Oxide Synthase in Cochlea of Normal Guinea Pigs[J]. Journal of China Medical University, 2000, 29(3): 180-181 |
| |
| Authors: | Shen Jing Tang Hao Zhang Xiaofang Zhang He Zhang Tiemin |
| |
| Abstract: | Objective:This paper was to study the distribution of inducible nitric oxide synthase (iNOS) in cochlea of normal guinea pigs. Methods:The expression of iNOS was measured with ABC immunohistochemical staining combined with image quantitative analysis technique on frozen sections from cochlea of normal guinea pigs. Results: iNOS staining were observed in the stria vascularis, spiral ganglion cells, outer and inner hair cells of Corti's organ as well as nerve fibers in normal cochlea. Conclusion: iNOS was expressed under physiological conditions in cochlea of guinea pigs. This result suggested that iNOS may be involved in physiological functions in cochlea. |
| |
| Keywords: | inducible nitric oxide synthase cochlea guinea pig immunohistochemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
