The effect of drug holidays in an animal model of tardive dyskinesia |
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Authors: | J. Bannet R. H. Belmaker R. P. Ebstein |
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Affiliation: | (1) Dept. of Psychiatry, Hadassah-Hebrew University Hospital, Jerusalem, Israel;(2) The Jerusalem Mental Health Center-Ezrath Nashim, P.O.B. 140, Jerusalem, Israel |
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Abstract: | Intermittent haloperidol treatment in mice increased 3H-spiroperidol binding to the same degree as continual haloperidol feeding. The results do not support the concept that drug holidays can reduce the incidence of tardive dyskinesia. |
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Keywords: | Dopamine Receptors Haloperidol Tardive dyskinesia |
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