| 淋巴芯片技术及其应用研究进展 |
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| 引用本文： | 陈喜林,张伟京. 淋巴芯片技术及其应用研究进展[J]. 中国实验血液学杂志, 2003, 11(5): 553-556 |
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| 作者姓名： | 陈喜林 张伟京 |
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| 作者单位： | 军事医学科学院附属医院淋巴肿瘤科,北京,100039 |
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| 摘 要： | 淋巴芯片是在基因芯片技术基础上发展起来的专门用于研究恶性淋巴瘤的生物芯片。本简要介绍了淋巴芯片的基本原理、制备的技术流程和不同类型，并着重介绍了淋巴芯片技术在恶性淋巴瘤诊断、分型及探讨发病机制等应用方面取得的进展及存在的问题。
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| 关 键 词： | 基因芯片 淋巴芯片 基因表达 恶性淋巴瘤 |
| 文章编号： | 1009-2137(2003)05-0553-04 |
| 修稿时间： | 2003-02-13 |
Advance in Research on Lymphochip Technology and Its Application--Review |
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| CHEN Xi-Lin,ZHANG Wei-Jing. Advance in Research on Lymphochip Technology and Its Application--Review[J]. Journal of experimental hematology, 2003, 11(5): 553-556 |
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| Authors: | CHEN Xi-Lin ZHANG Wei-Jing |
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| Affiliation: | Department of Oncology, Affiliated Hospital, Academy of Military Medical Sciences, Beijing 100039, China. |
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| Abstract: | The lymphochip is a special DNA chip which is u sed to monitor the gene expression profiling of malignant lymphoma. The basic principle, technological procedure and types of lymphochip were briefly reviewed in the article. The ar ticle emphatically introduced the advance of lymphochip implication which was us ed to identify the molecular diagnosis, distinguish the subtypes and research th e morbific mechanism of malignant lymphoma. The aspects of development and probl ems in lymphochip study were discussed. |
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| Keywords: | gene chip lymphochip gene expression malignant l ymphoma |
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