雌激素与颞下颌关节紊乱病

颞下颌关节紊乱病的流行病学调查发现女性患病率高于男性,且存在年龄分布,使得雌激素在其发病机制中的作用引起学者的注意。雌激素能够影响颞下颌关节组织结构如骨、软骨、关节盘等多种组织的生长、代谢、改建重建等,并能影响疼痛的调节机制,从而可能在颞下颌关节紊乱病的病理生理过程中起作用。

Estrogen and temporomandibular disorders

Epidemiologic literatures suggest that temporomandibular joint disorders(TMD) is more prevalent in women than in men. The severity of symptoms is also related to the age of the patients. The gender and age distribution of TMD suggests a possible link between its pathogenesis and estrogen. It has been reported that estrogen could influence the development, restitution and metabolism of the temporomandibular joint and associated structures such as bone, cartilage and articular disc. Estrogen can also influence the regulative mechanism of pain. Therefore estrogen maybe play a role in the pathophysiology of TMD.