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| 674例药品不良反应/事件报告分析 | |
| 引用本文： | 柏燕军,金锋,刘静,张颖,苑秋菊,李馨龄.674例药品不良反应/事件报告分析[J].中国药物警戒,2010,7(6):372-374. |
| 作者姓名： | 柏燕军 金锋 刘静 张颖 苑秋菊 李馨龄 |
| 作者单位： | 1. 中国中医科学院西苑医院,北京,100091 2. 吉林省食品药品评价中心,吉林,长春,130062 3. 国家食品药品监督管理局药品评价中心,北京,100045 |
| 摘 要： | 目的探讨我院药品不良反应/事件（ADR/ADE）发生的一般规律及特点,为临床合理用药提供参考。方法对我院2005年1月～2008年12月收集到的674例ADR报告,分别从患者性别、年龄、药品种类、ADR累及的系统-器官及临床表现等方面进行统计、分析。结果 674例中,以抗感染药物引起ADR最多（44.81%）,其次是中药制剂（29.08%）;ADR/ADE临床表现以皮肤及其附件损害占多数（35.32%）。结论抗感染药、中药制剂的不合理应用及静脉给药方式是导致药品不良反应/事件发生的主要原因,应加强其使用的监督管理。 |
| 关 键 词： | 药品不良反应/事件 报告 分析 |
Analysis of 674 Adverse Drug Reaction Reports |
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| BAI Yan-jan,JIN Feng,LIU Jing,ZHANG Ying,YUAN Qiu-ju,LI Xin-ling.Analysis of 674 Adverse Drug Reaction Reports[J].Chinese JOurnal of Pharmacovigilance,2010,7(6):372-374. | |
| Authors: | BAI Yan-jan JIN Feng LIU Jing ZHANG Ying YUAN Qiu-ju LI Xin-ling |
| Institution: | 1Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing 100091,China; 2Jilin Center for Drug Reevaluation,JLFDA,Jilin Changchun 130062,China; 3Center for Drug Reevaluation,SFDA,Beijing 100045,China) |
| Abstract: | Objective To study the general pattern and characteristics of adverse drug reaction/event（ADR/ADE） occurred in our hospital for references of rationaI drug use. Methods A total of 674 ADR/ADE cases collected from Janury 2005 to December 2008 were analyzed statistically in respect of patients＇age and sex,drug variet,clinical manifestations,ADR involved organs or systems. Results In the 674 ADR/ADE cases,mainly anti-infective drugs（44.18%）,followed by Traditional Chinese Medcines（29.08%）. The ADR/ADE were chiefly characterized by the lesions of skin and appen-dants（35.32%）. Conclusion The incidence of ADR/ADE can be reduced by strengthening monitoring of ADR and mastering the law of ADR occurrence. |
| Keywords: | adverse drug reaction/event report analysis |
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