|
|||||
|
|
The morphology and distribution of peptide-containing neurons in the adult and developing visual cortex of the rat. III. Cholecystokinin |
|
| Authors: | J K McDonald J G Parnavelas A N Karamanlidis G Rosenquist N Brecha |
| Affiliation: | (1) Department of Cell Biology, The University of Texas Health Science Center, 75235 Dallas, Texas, USA;(2) Department of Physiology, The University of Texas Health Science Center, 75235 Dallas, Texas, USA;(3) Department of Anatomy, Veterinary School, University of Thessaloniki, Greece;(4) Department of Physiology, University of California at Davis, School of Medicine, Davis, California, USA;(5) Center for Ulcer Research and Education, Veterans Administration Center-Wadsworth, Los Angeles, California, USA |
| Abstract: | Summary Immunocytochemistry was used to examine the morphology and distribution of cholecystokinin-like immunoreactive neurons in the visual cortex of the developing and mature albino rat. In the adult, labelled neurons were observed in all cortical layers but were concentrated in layers II and III. The majority of these neurons exhibited morphological features characteristic of bitufted and multipolar non-pyramidal cells described in Golgi preparations.Cholecystokinin immunoreactivity was first observed on postnatal day 3 and was confined to a few immature non-pyramidal cells located in the subplate region. The number of stained cells increased markedly during the latter part of the first postnatal week and by day 8 they were present in all cortical layers. Their morphological maturation occurred gradually during the first three weeks of postnatal life with the exception of a period of pronounced growth during the latter part of the second postnatal week. |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |