New 23-valent pneumococcal vaccine in relation to pneumococcal serotypes in systemic and non-systemic disease |
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| Authors: | L.E. Smart A.J. Dougall R.W.A. Girdwood |
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| Affiliation: | 1. Department of Pulmonology, St. Antonius Hospital, Nieuwegein, The Netherlands;2. Department of Medical Microbiology and Immunology, St. Antonius Hospital, Nieuwegein, The Netherlands;3. Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands;4. Department of Science, University College Roosevelt, Middelburg, The Netherlands |
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| Abstract: | The serotype distribution of 3631 strains of Streptococcus pneumoniae, isolated from various specimens obtained from patients was determined by coagglutination and included serotyping within a total of 13 serogroups. The results of serotyping of isolates from Scotland demonstrated that the new 23-valent pneumococcal vaccine includes serotypes which accounted for 91% strains associated with systemic disease and 79% strains isolated from other anatomical sites. Altogether, 114 strains (3.1%) were not typable because they did not possess a type-specific capsule; these were commonly isolated from eyes (12%). |
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