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放射性皮炎的发生机制及药物防治现状
作者姓名:戚霞露  吴亮  张陆勇
作者单位:1. 中国药科大学,江苏省新药筛选重点实验室,江苏 南京 210009;2. 中国药科大学,江苏省新药筛选重点实验室,江苏 南京 210009;广东药科大学药学院,新药筛选与药效学评价中心,广东 广州 510006
摘    要:放射性皮炎是肿瘤放疗过程中十分常见的并发症,会导致放疗中断,影响放疗效果.近年来对放射性皮炎的预防和治疗方法有了很多新的进展,现将放射性皮炎的发病机制和药物防治研究做一综述,为临床治疗和科学研究提供一定的理论依据.

关 键 词:放射治疗  自由基  放射性皮炎  抗氧化剂

Mechanism of radiodermatitis and current situation of prevention and treatment
Authors:QI Lulu  WU Liang and ZHANG Luyong
Institution:1.Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University,Nanjing 210009,China;2.Center for Drug Screening and Pharmacodynamics Evaluation,School of Pharmacy,Guangdong Pharmaceutical University,Guangzhou 510006,China,1.Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University,Nanjing 210009,China;2.Center for Drug Screening and Pharmacodynamics Evaluation,School of Pharmacy,Guangdong Pharmaceutical University,Guangzhou 510006,China and 1.Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University,Nanjing 210009,China;2.Center for Drug Screening and Pharmacodynamics Evaluation,School of Pharmacy,Guangdong Pharmaceutical University,Guangzhou 510006,China
Abstract:Radiodermatitis is a common complication of tumor radiotherapy leading to interruption or termination of radiotherapy.In recent years,there have been many new research progress for the prevention and treatment of radiodermatitis.This paper reviewed the mechanism of radiodermatitis and declared the current situation of its prevention and treatment.
Keywords:Radiotherapy  Free radical  Radiodermatitis  Antioxidants
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