110例婴儿巨细胞病毒肝炎分析

目的：探讨婴儿巨细胞病毒肝炎的检测方法和临床特征。方法：收集110例婴儿巨细胞病毒肝炎患儿的检验数据及临床资料，比较乳汁中CMV-DNA定量检测与患儿黄疸的关系；以尿CMV-DNA定量检测为标准，与血CMV-DNA定量及血CMV-IgM检测比较；比较CMV-DNA检测及血清特异性抗体检测的临床意义。结果：婴儿巨细胞肝炎主要表现为黄疸、肝脾大及伴随症状；乳汁CMV-DNA阳性患儿TB、DB较高（P<0.05）；与尿CMV-DNA比较，血CMV-DNA定量及血CMV-IgM检测的阳性率较低（P<0.05）；CMV-DNA检测及血清特异性抗体检测的对判断该疾病严重程度的指导意义不大。结论：婴儿巨细胞病毒肝炎临床特征无特异性，以黄疸最常见；诊断需结合临床及多种实验室检测结果。

The clinical research of 110 cases with cytomegalovirus Infantile cytomegalovirus hepatitis

Objective:To discuss the detection method and clinical features in baby cytomegalovirus infantile cytomegalovirus hepatitis. Methods:collected 110 cases testing data and clinical data in baby patients for baby CMV ICH's , To compare the relationship between CMV-DNA quantitative detection in breast milk and baby jaundice. The standard is CMV-DNA quantitative detection in urine. To compare with CMV-DNA and CMV-IgM quantitative in blood, CMV-DNA detection and serum specificity antibody have clinical significance. Results:The main expression for baby CMV ICH is jaundice, liver and spleen swelling, simultaneous phenomenon. Baby for CMV-DNA in breast milk positive, have the high TB and DB (P<0.05).To compare with CMV-DNA in urine, quantitative for CMV-DNA and CMV-IgM in blood have lower positive (P<0.05).CMV-DNA and serum specificity antibody not have guiding significance to estimate this disease's severity. Conclusion:Clinical features for baby CMV ICH has no specific feature. The most common is jaundice .Diagnosis should combine clinic with a variety of laboratorial inspection results.