Osteomyelitis following Bacille Calmette-Guerin vaccination |
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| Authors: | Al-Jassir Fawzi F Aldeeri Riyadh A Alsiddiky Abdul-Monem M Zamzam Mohamed M |
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| Institution: | Department of Orthopedics, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia. |
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| Abstract: | Secondary complications after Bacille Calmette-Guerin (BCG) vaccination are unusual. We describe 3 immunocompetent children who developed osteomyelitis after BCG vaccination. The course of the disease is not dramatic, but marked changes are frequently visible in plain radiograph and MRI. The real-time polymerase chain reaction has an essential role to confirm the diagnosis of BCG osteomyelitis. With proper surgical intervention and chemotherapy, the prognosis is usually good. |
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