| 胃癌患者EBV感染潜伏基因产物表达的研究 |
| |
| 引用本文： | 李淑英,朱丽华,夏庆安,周天戟. 胃癌患者EBV感染潜伏基因产物表达的研究[J]. 陕西医学杂志, 2006, 35(7): 831-832 |
| |
| 作者姓名： | 李淑英 朱丽华 夏庆安 周天戟 |
| |
| 作者单位： | 1. 华北煤炭医学院生物系,唐山,063000
2. 唐山市工人医院 |
| |
| 基金项目： | 教育部留学回国人员科研启动基金 |
| |
| 摘 要： | 目的:研究EBV阳性胃癌中潜伏基因产物EBV编码的小RNA(EBER1)及潜伏膜蛋白LM P1的表达状况。方法:原位杂交法检测胃癌患者石蜡包埋组织标本中EBER1;免疫组化法检测EBV阳性胃癌中LM P1。结果:217例胃癌患者癌组织标本中检测到23例EBER 1;EBV阳性胃癌中无潜伏感染膜蛋白LM P1表达。结论:EBV阳性胃癌中缺乏潜伏感染膜蛋白LM P1的表达。
|
| 关 键 词： | 胃肿瘤/免疫学 疱疹病毒科感染 基因表达 免疫组织化学 |
| 收稿时间： | 2005-10-19 |
| 修稿时间： | 2005-10-19 |
Study on gene products of EBV infection in castric carcinoma patients |
| |
| Li Shuying ,Zhu Lihua ,Xia Qingan ,et al. Study on gene products of EBV infection in castric carcinoma patients[J]. Shaanxi Medical Journal, 2006, 35(7): 831-832 |
| |
| Authors: | Li Shuying Zhu Lihua Xia Qingan et al |
| |
| Affiliation: | Tangshan 063000 |
| |
| Abstract: | Objective:To investigate the expression of EBER1 and LMP1 in gastric carcinoma patients of EBV Infections.Methods: EBER1 in 217 cases of gastric carcinoma was detected with In Situ Hybridization.Then,EBV positive cases were selected for analysis of the expression level of LMP1 by immunohistochemistry.Results: In 217 cases of gastric carcinoma,there were EBER1 positive 23 cases;The expressiones of LMP1 in EBV positive gastric carcinoma were not detected.Conclusions: There was no LMP1 expression in EBV positive Gastric carcinoma. |
| |
| Keywords: | Stomach Neoplasma/immunology Herpesviridae Infections Gene Expression Immunohistochemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
