黄腊果果皮化学成分的分离与鉴定

目的研究黄腊果果皮的化学成分。方法采用反复硅胶柱色谱法、Sephadex LH-20柱色谱法、重结晶和HPLC等方法进行分离纯化,并通过NMR技术鉴定其化学结构。结果从黄腊果中分离得到8个化合物,分别鉴定为:3-羟基-2-甲基-4-吡喃酮(3-hydroxy-2-methyl-4-pyrone,1)、芥子醛(sinapaldehyde,2)、2-甲基-4-吡喃酮-3-O-β-D-吡喃葡萄糖苷(2-methyl-4-pyrone-3-O-β-D-glucopyr-anoside,3)、3,5-二甲氧基-4-羟基苯甲酸-7-O-β-D-葡萄糖苷(3,5-dimethoxyl-4-hydroxybenzoic acid-7-O-β-D-glucopyranoside,4)、胡萝卜苷(daucosterol,5)、β-谷甾醇(sitosterol,6)、3-O-α-L-吡喃鼠李糖-(1→2)-α-L-吡喃阿拉伯糖-30-降甲基齐墩果-12,20(29)-二烯-28-羧酸(3-O-α-Lrhamnopyrano-syl-(1→2)-α-L-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid,7)、3-O-β-D-吡喃葡萄糖-(1→3)-α-L-吡喃鼠李糖-(1→2)-α-L-吡喃阿拉伯糖-30-降甲基齐墩果-12,20(29)-二烯-28-羧酸(3-O-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-D-glucopyranosyl-(1→3)-α-L-arabi-nopyranosyl-30-norolean-12,20(29)-dien-28-oic acid,8)。结论化合物1-4为首次从木通科植物中分离得到,化合物6-8为首次从黄腊果中分离得到。

Isolation and identification of chemical constituents from peels of Stauntonia brachyanthera Hand.Mazz.

Objective To study the chemical constituents from peels of Staunton iabrachyanthera Hand.Mazz..Methods The compounds were isolated by silica gel column,SephadexLH-20 column,recrystallization and HPLC method,their structures were confirmed on the basis of NMR analysis.Results Eight compounds were isolated and identified as 3-hydroxy-2-methyl-4-pyrone(1),sinapaldehyde(2),2-methyl-4-pyrone-3-O-β-D-glucopyranoside(3),3,5-dimethoxyl-4-hydroxybenzoic acid-7-O-β-D-glucopyranoside(4),daucosterol(5),sitosterol(6),3-O-α-L-rhamnopyranosyl-(1→2)-α-L-rhamnopyranosyl-30-norolean-12,20(29)-dien-28-oic acid(7),3-O-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid(8).Conclusions compounds 1-3 and 4 are firstly isolated from the Laidizabalaceae,while compounds 6-8 are isolated from this herb for the first time.