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Relationship between COX-2 and cell cycle-regulatory proteins in patients with esophageal squamous cell carcinoma |
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| Authors: | Huang Jun-Xing Xiao Wei Chen Wei-Chang Lin Mao-Song Song Zheng-Xiang Chen Ping Zhang Yun-Lei Li Feng-Yue Qian Rong-Yu Salminen Eeva |
| Affiliation: | Department of Oncology, The People's Hospital of Taizhou, Taizhou Medical School, Yangzhou and Nantong University, No. 210, Yingchun Road, Taizhou 225300, Jiangsu Province, China. huangjunxing@yahoo.com.cn |
| Abstract: | AIM: To investigate the correlation between cyclooxygenase-2 (COX-2) and cell cycle-regulatory proteins in patients with esophageal squamous cell carcinoma (ESCC). METHODS: One hundred and two surgically obtained specimens of ESCC were randomly collected. All specimens were obtained from patients who had not received chemoor radiotherapy prior to surgical resection.Twenty-eight specimens of normal squamous epithelium served as controls. The expression of COX-2, Ki-67, cyclin A and p27 was examined by immuno... |
| Keywords: | Esophageal squamous cell carcinoma Cyclooxygenase-2 Ki-67 Cyclin A p27 Tumor markers Immunohistochemistry |
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