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| Immune phenotype in children with therapy-nave remitted and relapsed Crohn’s disease | |
| 作者姓名： | Cseh A Vasarhelyi B Molnar K Szalay B Svec P Treszl A Dezsofi A Lakatos PL Arato A Tulassay T Veres G |
| 作者单位： | Research Group for Pediatrics and Nephrology Semmelweis University Hungarian Academy of Sciences Department of Laboratory Medicine First Department of Pediatrics First Department of Medicine |
| 摘 要： | AIM: To characterize the prevalence of subpopulations of CD4+ cells along with that of major inhibitor or stimulator cell types in therapy-nave childhood Crohn's disease (CD) and to test whether abnormalities of immune phenotype are normalized with the improvement of clinical signs and symptoms of disease. METHODS: We enrolled 26 pediatric patients with CD. 14 therapy-nave CD children; of those, 10 children remitted on conventional therapy and formed the remission group. We also tested another group of 12... |
| 关 键 词： | Crohn’s disease Dendritic cell Infliximab Lymphocyte Monocyte Regulatory T cell Relapse Remission Therapy-nave Toll-like receptor |
| 收稿时间： | 2010-03-01 |
| 本文献已被 维普 PubMed 等数据库收录！ | |