| 肿瘤标记物蛋白芯片对肺癌的诊断价值 |
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| 引用本文： | 林海龙,崔社怀,曹国强,梁先万,康军. 肿瘤标记物蛋白芯片对肺癌的诊断价值[J]. 第三军医大学学报, 2005, 27(15): 1591-1592 |
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| 作者姓名： | 林海龙 崔社怀 曹国强 梁先万 康军 |
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| 作者单位： | 第三军医大学大坪医院野战外科研究所呼吸内科,重庆,400042;第三军医大学大坪医院野战外科研究所呼吸内科,重庆,400042;第三军医大学大坪医院野战外科研究所呼吸内科,重庆,400042;第三军医大学大坪医院野战外科研究所呼吸内科,重庆,400042;第三军医大学大坪医院野战外科研究所呼吸内科,重庆,400042 |
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| 摘 要： | 目的研究肿瘤标记物蛋白芯片对肺癌的诊断价值.方法将96例已经确诊的病例分为肺癌组和非肺癌组,采用蛋白芯片测量技术检测肺癌组和非肺癌组其血清肿瘤标记物.结果①肺癌组和非肺癌组12项标记物中糖链抗原19-9(CA19-9),神经元特异性烯醇化酶(NSE),癌胚抗原(CEA),糖链抗原242(CA242)癌抗原125(CA125)、铁蛋白6项测定值差异有显著性(P＜0.01).②肺癌组和非肺癌组12项标记物阳性检测中6项测定阳性率差异有显著性(P＜0.01).其中肺癌组CEA,CA242和CA 125呈现高阳性检测率.结论肿瘤标记物蛋白芯片对肺癌的诊断有重要的价值.
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| 关 键 词： | 肺癌 肿瘤标记物 蛋白芯片 |
| 文章编号： | 1000-5404(2005)15-1591-02 |
| 收稿时间： | 2005-01-25 |
| 修稿时间： | 2005-07-07 |
Diagnostic value of protein-chip by detecting tumor markers for lung cancer |
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| LIN Hai-long,CUI She-huai,CAO Guo-qiang,LIANG Xian-wan,Kang Jun. Diagnostic value of protein-chip by detecting tumor markers for lung cancer[J]. Acta Academiae Medicinae Militaris Tertiae, 2005, 27(15): 1591-1592 |
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| Authors: | LIN Hai-long CUI She-huai CAO Guo-qiang LIANG Xian-wan Kang Jun |
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| Abstract: | Objective To investigate the role of protein-chip by detecting the changes of tumor markers for diagnosis of lung cancer. Methods A total of 96 patients with definite diagnosis were divided into 2 groups: lung cancer group (n=48) and control group (n=48). Using the protein-chip technique, the twelve tumor markers were detected into the two groups. Results The serum content of in measuring value of CA19-9, NSE, CEA, CA242, Ferritin, CA125 in the twelve tumor markers showed statistical significance between two groups (P<0.01) and CEA, CA242 and CA125 had high positive rates in lung cancer group. Conclusion Detecting tumor markers by protein-chip has an important value in diagnosis of lung cancer. |
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| Keywords: | lung cancer tumor markers protein-chip |
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