| 钠-氢交换蛋白的研究进展 |
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| 引用本文： | 周慧芬,刁路明,赵红刚. 钠-氢交换蛋白的研究进展[J]. 医学综述, 2008, 14(19): 2893-2894 |
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| 作者姓名： | 周慧芬 刁路明 赵红刚 |
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| 作者单位： | 1. 武汉大学基础医学院,武汉,430000
2. 咸宁学院医学院病理学教研室,湖北,咸宁,437100 |
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| 摘 要： | 钠-氢交换蛋白质是维持细胞内环境的主要细胞膜蛋白质之一,其主要功能是调节细胞内pH值,使之保持在生理范围之内。细胞内pH值的变化,直接或间接的影响细胞的生长、分裂、增殖、分化和死亡,以及细胞的移动和肿瘤细胞的转移。
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| 关 键 词： | 肿瘤 钠-氢交换蛋白 肿瘤治疗 |
Study Progress of Na~+H~+ Exchanger Protein |
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| ZHOU Hui-fen,DIAO Lu-ming,ZHAO Hong-gang. Study Progress of Na~+H~+ Exchanger Protein[J]. Medical Recapitulate, 2008, 14(19): 2893-2894 |
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| Authors: | ZHOU Hui-fen DIAO Lu-ming ZHAO Hong-gang |
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| Affiliation: | ZHOU Hui-fen1,DIAO Lu-ming1,ZHAO Hong-gang2.(1.School of Basic Medical Science,Wuhan University,Wuhan 430000,China,2.Department of Pathology,Medical College of Xianning University,Xianning 437100,China) |
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| Abstract: | Na^＋/H^＋ Exchanger （NHE） protein is one of the main membrane proteins to maintain cellular internal environment： The primary function of NHE is to adjust intra-cellular PH value keeping in normal physical range. The pH value variation in cells has effects on the cells＇ growth, cleavage, generation, differentiation and death directly or indirectly,even on the cells＇ ambulation and tumour cell＇s metastasis. |
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| Keywords: | Tumor Na+/H+ exchanger protein Tumor therapy |
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