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CD8‐positive peripheral T‐cell lymphoma with aberrant expression of CD20 and concurrent in situ follicular lymphoma
Authors:Amaia Sagasta  Ricardo Molina‐Urra  Daniel Martinez  Blanca Gonzalez‐Farre  Esther Marti  Maria Jose Herranz  Teresa Estrach  Elias Campo  Lluis Colomo
Abstract:A case of a 78‐year‐old woman with a CD8‐positive peripheral T‐cell lymphoma with aberrant expression of CD20 associated with follicular lymphoma in situ (FLIS) is reported. The neoplasm presented initially as cutaneous macules, papules, plaques and nodules. A skin biopsy was performed and the diagnosis of peripheral T‐cell lymphoma (PTCl) with aberrant expression of CD20 was made. The staging procedures included an excisional inguinal lymph node biopsy that showed findings similar to those of the previous diagnosis. In addition, FLIS was identified. The clinicopathologic features of PTCLs with aberrant CD20 expression involving the skin as well as this uncommon association are reviewed.
Keywords:CD20  cutaneous T‐cell lymphoma  follicular lymphoma  FLIS
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