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温郁金茎叶化学成分研究
引用本文:王利霞,邓志威,黄可新,林文翰.温郁金茎叶化学成分研究[J].中国中药杂志,2008,33(7):785-788.
作者姓名:王利霞  邓志威  黄可新  林文翰
作者单位:1. 温州医学院,药学院,中药系化学教研室,浙江,温州,325035
2. 北京师范大学,分析测试中心,北京,100075
3. 北京大学,天然药物与仿生药物国家重点实验室,北京,100083
摘    要:目的:研究温郁金Curcuma wenyujin地上茎叶部分的化学成分。方法:采用硅胶、Sephadex LH-20等色谱方法进行分离、纯化,通过理化性质及波谱方法鉴定其化学结构。结果:从温郁金95%乙醇提取物的石油醚部分分离得到9个倍半萜类化合物,分别为:莪术二酮(curdione,1),新莪术二酮(neocurdione,2),反,反吉马酮(trans,trans-germacrone,3),顺,反吉马酮(cis,trans-germacrone,4),郁金烯酮(curcumenone,5),郁金二酮(curcumadione,6),异原郁金醇(isoprocurcumenol,7),欧亚活血丹内酯(glechomanolide,8),和二氢莪术二酮(1R,10R)-(-)-1,10-dihydrocurdione,9]。结论:以上9个化合物均为首次从该植物地上茎叶部分分离得到。

关 键 词:温郁金  化学成分  倍半萜
收稿时间:8/9/2007 12:00:00 AM

Sesquiterpenes from stems and leaves of Curcuma wenyujin
WANG Li-xia ;DENG Zhi-wei ;HUANG Ke-xin ;LIN Wen-han.Sesquiterpenes from stems and leaves of Curcuma wenyujin[J].China Journal of Chinese Materia Medica,2008,33(7):785-788.
Authors:WANG Li-xia ;DENG Zhi-wei ;HUANG Ke-xin ;LIN Wen-han
Institution:School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou 325035, China.
Abstract:Objective:To study the chemical constituents of the stem and leaves from Curcuma wenyujin.Method:The compounds were isolated by silica gel column chromatography in associating with Sephadex LH-20 chromatography.While their structures were identified on the basis of spectroscopic date.Result:Nine sesquiterpenes were isolated and identified.Their structures were identified as curdione(1),neocurdione(2),trans,trans-germacrone(3),cis,trans-germacrone(4),curcumenone(5),curcumadione(6),isoprocurcumenol(7),glechomanolide(8)and(1R,10R)-(-)-1,10-dihydrocurdione(9).Conclusion:All of these compounds were isolated from the stems and leaves of this plant for the first time.
Keywords:Curcuma wenyujin  chemical constituents  sesquiterpenes
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