术后PCEA对腹部手术患者应激反应的影响

目的：研究病人自腔硬膜外镇痛（PCEA）对腹部手术患者应激反应的影响。方法：选择88例腹部手术患者随机分为两组：PCEA组（A）和非PCEA组（B），对患者术后的镇痛效果以及患者术前，术后应激反应的部分指标；白细胞计数，C－反应蛋白，血糖，前白蛋白和皮质醇进行观察。结果：（1）PCEA组镇痛效果良好，患者满意度高（P＜0．01）；（2）术前各项指标无差异，血清白细胞计数，C－反应蛋白，血糖和皮质醇浓度A组均明显低于B组（P＜0．05），前白蛋白浓度A组明显高于B组（P＜0．05）。结论：术后PCEA能抑制机体的应激反应，稳定内环境，有利于腹部手术患者术后机体的康复。

Effects of Postoperative Patient-Controlled Epidural Analgesia (PCEA) on Stress Response to Abdominal Surgery

ve:To evaluate the effects of postoperative PCEA on stress response to abdominal surgery. Methods:88 patients undergoing abdominal surgery were randomly divided into group A (PCEA) and group B(non-PCEA). Postoperative analgesic effects and perioperative parameters such as leukocyte count, C-reaction protein, glucose, Prealbumin and corticosteroid in blood were determined and analyzed. Results:The analgesic effect of group A was better than that of group B. The postoperative leukocyte count, the serum concentrations of C-reaction protein, glucose and corticosteroid in group A were significantly lower than those in group B , while the serum level of prealbumin in group A was significantly higher than that in group B. Conclusion : Postoperative PCEA leads to a better analgesic effect. It can reduce stress response and stablize the inner-circumstance, so it is propitious to patients recovery.