Accelerated nodulosis during methotrexate therapy in a patient with systemic lupus erythematosus and Jaccoud's arthropathy |
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| Authors: | Rivero M-G Salvatore A-J Gómez-Puerta J A Mascaró J M Cañete J D Muñoz-Gómez J Sanmartí R |
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| Institution: | Department of Immunology, Hospital Central, 1 Department of Internal Medicine, Hospital Lagomaggiore, Mendoza, Argentina, 2 Department of Rheumatology, 3 Department of Dermatology, Hospital Clínic, Barcelona, Spain. |
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| Abstract: | SIR, Accelerated nodulosis (AN) is a well-known complicationof methotrexate (MTX) therapy in rheumatoid arthritis (RA) patients1], characterized by the rapid appearance of small noduleson the hands, elbows and feet 1]. Although subcutaneous noduleshave been described in systemic lupus erythematosus (SLE) 2–5],we are unaware of reports of AN in SLE during MTX treatment. We report the case of a 34-yr-old female who was referred inOctober 1994 to a rheumatology department |
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