| Endoxin-mediated myocardial ischemia reperfusion injury in rats in vitro |
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| 作者姓名： | 柯永胜 汪和贵 王德国 张根葆 |
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| 作者单位： | Department of Cardiology Yijishan Hospital，Wannan Medical College，Department of Cardiology Yijishan Hospital，Wannan Medical College，Department of Cardiology Yijishan Hospital，Wannan Medical College，Department of Cardiology Yijishan Hospital，Wannan Medical College Wuhu，China，Wuhu，China，Wuhu，China，Wuhu，China |
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| 摘 要： | Endoxin-mediated myocardial ischemia reperfusion injury in rats in vitro@柯永胜$Department of Cardiology Yijishan Hospital,Wannan Medical College!Wuhu,China
@汪和贵$Department of Cardiology Yijishan Hospital,Wannan Medical College!Wuhu,China
@王德国
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| 关 键 词： | 心肌疾病 缺血再灌注损伤 小鼠 动物实验 药物治疗 |
Endoxin-mediated myocardial ischemia reperfusion injury in rats in vitro |
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| KeYS WangHG WangDG ZhangGB.Endoxin-mediated myocardial ischemia reperfusion injury in rats in vitro[J].Acta Academiae Medicinae Wannan,2005,24(2):157. |
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| Authors: | KeYS WangHG WangDG ZhangGB |
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| Institution: | DepartmentofCardiology,YijishanHospital,WannanMedicalCollege,Wuhu,China |
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| Abstract: | Myocardial ischemia reperfusion results in an increase in intracellular sodium concentration, which secondarily increases intracellular calcium via Na^ -Ca2^ exchange, resulting in cellular injury. Endoxin is an endogenous medium of digitalis receptor and can remarkably inhibit Na^ /K^ -ATPase activity. Although the level of plasma endoxin is significantly higher during myocardial ischemia, its practical significance is unclear. |
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| Keywords: | endoxin anti-digoxin antiserum myocardial reperfusion injury morphological evaluation Na~ /K~ -exchanging ATPase |
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