| 氯胺酮+异丙酚辅助小儿骶管阻滞麻醉的临床观察 |
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| 引用本文： | 赵锁良,林红艳,李国宏. 氯胺酮+异丙酚辅助小儿骶管阻滞麻醉的临床观察[J]. 社区医学杂志, 2007, 5(13): 10-12 |
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| 作者姓名： | 赵锁良 林红艳 李国宏 |
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| 作者单位： | 赵锁良 (陕西省扶风胜利医院麻醉科,陕西宝鸡,722200)； 林红艳 (深圳市公明人民医院麻醉科,广东深圳,518106)； 李国宏 (深圳市公明人民医院麻醉科,广东深圳,518106)； |
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| 摘 要： | 目的观察小儿骶管阻滞麻醉辅助氯胺酮+异丙酚的安全性及效果,并与单纯辅助氯安酮或异丙酚作比较。方法选择下腹部、会阴部、下肢手术患儿105例,ASAⅠ~Ⅱ级,年龄1~7岁,在基础麻醉下行骶管阻滞,随机分为三组辅助用药(用微泵持续输注):Ⅰ组,氯胺酮25μg.kg-1.min-1;Ⅱ组,异丙酚120μg.kg-1.min-1;Ⅲ组,氯胺酮10μg.kg-1.min-1+异丙酚45μg.kg-1.min-1。结果三组综合麻醉效果满意,均能满足手术要求;术中镇静评分Ⅰ组4.23±0.6,Ⅱ组3.95±0.5,Ⅲ组4.12±0.6,组间无明显差异(P>0.05);注药后2 min HR、MAP、SpO2变化有明显差异;术后苏醒时间Ⅰ组明显长于Ⅱ、Ⅲ组(P<0.05);苏醒期恶心呕吐、精神症状、躁动不安等不良反应的发生率Ⅲ组明显少于Ⅰ、Ⅱ组(P<0.05)。结论氯胺酮+异丙酚辅助小儿骶管阻滞麻醉效果可靠,安全性高,不良反应少于单纯应用氯胺酮或异丙酚辅助小儿骶管阻滞。
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| 关 键 词： | 骶管阻滞麻醉 氯胺酮 异丙酚 |
Clinical study of paediatric caudal block analgesia assisted with ketamine and propofol |
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| ZHAO Suoliang,LIN Hongyan,LI Guohong. Clinical study of paediatric caudal block analgesia assisted with ketamine and propofol[J]. journal of community medicine, 2007, 5(13): 10-12 |
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| Authors: | ZHAO Suoliang LIN Hongyan LI Guohong |
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| Abstract: | Objective To assess the analgesia effect and safety of paediatric caudal block analgesia assisted with ketamine and propofol.Methods One hundred and five paediatric patients(age:1～7years,ASA grade: Ⅰ～Ⅱdegree.) undertook caudal block analgesia.They were randomly divided into three groups according to different assisting drugs: group I(ketamine 25 μg.kg-1.min-1),group II(propofol 120 μg.kg-1.min-1) and group III(ketamine10 μg.kg-1.min-1+propofol 45 μg.kg-1.min-1).Results The effects of analgesia were all satisfied in three groups.The HR,MAP and SpO2 had no difference in 2 min after injection.The wake-up time was longer in group I(P<0.05).The rate of bad reactions,such as nausea,vomit,restlessness and mental symptom,was lower in group III(P<0.05).Conclusion It's a safety and effective block analgesia method by using ketamine and propofol. |
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| Keywords: | Caudal block analgesia Ketamine Propofol |
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