The human chorionic gonadotropin molecule from patients with trophoblastic diseases has a high thyrotropic activity but is less active in the ovary |
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| Authors: | K Kato MH Mostafa K Mann AE Schindler R Hoermann |
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| Affiliation: | 1. Department of Obstetrics and Gynecology, University of Essen, Essen, Germany;2. Division of Endocrinology, Department of Medicine, University of Essen, Essen, Germany |
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| Abstract: | To examine the pathogenesis of hyperthyroidism in women with trophoblastic diseases, the biological activity of human chorionic gonadotropin (hCG) molecules in women with normal pregnancy (n?=?85) and in women with trophoblastic diseases (vesicular mole, n?=?30; and choriocarcinoma, n?=?12) was compared. Hyperthyroidism (thyroid stimulating hormone (TSH)
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