| 44例热化疗在卵巢癌中的临床观察分析 |
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| 引用本文： | 丁娟,符慧群.44例热化疗在卵巢癌中的临床观察分析[J].实用预防医学,2006,13(3):725-726. |
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| 作者姓名： | 丁娟 符慧群 |
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| 作者单位： | 中南大学湘雅三医院肿瘤科,湖南,长沙,410013 |
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| 摘 要： | 目的探讨热化疗对于晚期卵巢癌的近期治疗效果,3年生存率和毒副反应的影响。方法44例晚期卵巢癌患者均经过手术病理分期,随机分成热化疗组和化疗组,比较两组的近期疗效,3年生存率和毒副反应的发生率。结果热疗组的近期疗效明显高于化疗组(P<0.05)。热疗组的3年生存率为65%高于化疗组(48%),但没有统计学上的差异。两组毒副反应的发生率相似,症状轻微,可以耐受。结论热化疗治疗卵巢癌患者有好的近期疗效,毒副反应小,有望提高晚期卵巢癌患者的5年生存率。
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| 关 键 词： | 热疗 化疗 恶性卵巢肿瘤 |
| 文章编号： | 1006-3110（2006）03-0725-02 |
| 收稿时间： | 2006-02-23 |
| 修稿时间： | 2006年2月23日 |
Observation on Hyperthermia Combined Chemotherapy in Treatment of Ovarian Carcinoma |
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| DING Juan,FU Hui-qun.Observation on Hyperthermia Combined Chemotherapy in Treatment of Ovarian Carcinoma[J].Practical Preventive Medicine,2006,13(3):725-726. |
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| Authors: | DING Juan FU Hui-qun |
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| Institution: | Department of Oncology, the Third Xiangya Hospital, Central South University, Changsha 410013, Hunan, China |
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| Abstract: | Objective To investigate the clinical effect of adjuvant treatment for ovarian carcinoma with hyperthermia combined chemotherapy. Methods Forty-four patients with late ovarian carcinoma received surgical resection and pathological staging were randomized 23 patients to receive adjuvant hyperthermia and chemotherapy, and 21 patients to receive conventional chemotherapy alone; and the short-term effect, 3-year survival rates and adverse side effects were compared. Results Patients received hyperthermia and chemotherapy resulted in better outcomes as compared with chemotherapy alone in the short-term effect and the 3-year survival rates, but only the short-term effect reached significant difference (P<0.05). The side effects between these two groups were similar. Conclusion Adjuvant hyperthermia combined with chemotherapy is effective in the treatment of ovarian carcinoma, and the side effects are tolerable. |
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| Keywords: | Hyperthermia Chemotherapy Ovarian Carcinoma |
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