Gastric Bypass in a Japanese Man with Prader-Willi Syndrome and Morbid Obesity |
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| Authors: | Junji Kobayashi Masaaki Kodama Kazuma Yamazaki Okamichi Morikawa Shunichi Murano Norifumi Kawamata Isao Kawamura |
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| Institution: | (1) Department of Internal Medicine, Shimotsuga General Hospital, Japan;(2) Department of Surgery, Shimotsuga General Hospital, Japan;(3) Department of Surgery, Shimotsuga General Hospital, Japan;(4) Department of Surgery, Shimotsuga General Hospital, Japan;(5) Department of Internal Medicine, Shimotsuga General Hospital, Japan;(6) Division of Endocrinology and Metabolism, Department of Medicine, Jichi Medical School, Japan;(7) Department of Surgery, Shimotsuga General Hospital, Japan |
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| Abstract: | Background: In Prader-Willi syndrome (PrWS), marked obesity is the most serious and common complication, contributing significantly
to morbidity and mortality. Because of the associated psychosocial difficulties, bariatric surgery appears to be the only
effective treatment. Case Report: A 30-year-old man with PrWS weighing 108 kg (BMI 50 kg/m2), underwent Roux-en-Y gastric bypass (RYGBP). 3 months before the RYGBP, he weighed 146 kg (BMI 68.5), partly because of
heart failure. 18 months after RYGBP, he weighed 92.4 kg (BMI 43.3), with no postoperative complications. Moreover, he showed
considerable increase in serum HDL-cholesterol levels with reciprocal reduction in LDL-cholesterol after the surgery. Conclusion:
RYGBP resulted in satisfactory weight loss and improvement in serum lipid profile in a Japanese morbidly obese patient with
PrWS. |
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| Keywords: | PRADER-WILLI SYNDROME MORBID OBESITY BARIATRIC SURGERY GASTRIC BYPASS HIGH DENSITY LIPOPROTEIN |
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