成人甲状腺结构及碘营养状况与性别和年龄的相关性研究

目的调查我省成人甲状腺结构及碘营养状况,分析其与性别、年龄的相关性。方法采用"人口比例概率抽样方法(PPS)",选取3645例纳入调查。年龄分组(A组:20~29岁、B组:30~39岁、C组:40~49岁、D组:50~59岁、E组:60~70岁)。行甲状腺超声检查及尿碘检测。甲状腺结构异常分组(结节性病变、弥漫性病变、弥漫性病变合并结节)。统计甲状腺结构及尿碘状况。结果女性甲状腺患病率高于男性,各结构异常占比均高于男性(P<0.001)。甲状腺患病率与年龄呈正相关,各年龄组比较差异有统计学意义(P<0.05)。甲状腺结构异常中结节性病变占比最高,不同性别、年龄组结构异常组内比较,结节性病变占比亦最高(P<0.001)。总体尿碘及男、女尿碘中位数均处于碘适宜水平。尿碘≥300μg/L甲状腺结构异常占比高于其余各组(P<0.05)。结论我省成人甲状腺结构异常及碘营养状况与性别、年龄有相关性,高碘营养人群甲状腺结构异常增加。

Correlation of Thyroid Structure and Iodine Nutrition Status With Sex and Age in Adults

Objective To investigate the thyroid structure and iodine nutritional status of adults in heilongjiang province,and to analyze the correlation between thyroid structure and gender and age.Methods The population proportional probability sampling(PPS)was used to select 3645 people.Age group(group A:20-29 years old,group B:30-39 years old,group C:40-49 years old,group D:50-59 years old,group E:60-70 years old).Ultrasonic examination of thyroid and urinary iodine were performed.Thyroid structural abnormalities were divided(nodular lesions,diffuse lesions,diffuse lesions with nodules).Statistics thyroid structure and urine iodine status.Results The prevalence of thyroid in women was higher than that in men,and the proportion of all structural abnormalities was higher than that in men(P<0.001).The prevalence of thyroid diseasewas positively correlated with age,and the differences among different age groups were statistically significant(P<0.05).The proportion of nodular lesions was the highest among the thyroid structural abnormalities,and the proportion of nodular lesions was also the highestamong the structural abnormalities of different genders and age groups(P<0.001).The total urinary iodine and the median of male and female urinary iodinewere at the appropriate level of iodine.The proportion of abnormal thyroid structure with urinary iodine≥300μg/L was higher than that of other groups(P<0.05).Conclusions The abnormal thyroid structure and iodine nutrition status of adults in heilongjiang province are correlated with gender and age,and the occurrence of thyroid diseases is related to high iodine nutrition.