气管镜介入治疗对良性气道狭窄患者的疗效及狭窄程度、气促评分的影响

目的探讨气管镜介入治疗对良性气道狭窄患者的疗效及狭窄程度、气促评分的影响。方法选取2016年5月～2018年10月我院及广东医科大学附属中山医院收治的良性气道狭窄患者30例,根据良性气道狭窄病因不同分为三组,分别为瘢痕组(13例)、肉芽肿组(12例)、良性肿瘤组(5例)。所有患者均进行气管镜介入治疗。比较三组患者疗效、气道狭窄程度、气促评分、肺功能。结果瘢痕组、良性肿瘤组的总有效率分别为84.6%、80.0%均高于肉芽肿组(75.0%)(P0.05);瘢痕组气道狭窄程度(1.4±0.5)%小于肉芽肿组(12.2±0.3)%、良性肿瘤组(14.9±0.6)%(P0.05),肉芽肿组、良性肿瘤组气道狭窄程度相比,无明显差异(P0.05),瘢痕组气促评分(1.1±0.4)分大于肉芽肿组(0.5±0.1)分、良性肿瘤组(0.3±0.1)分(P0.05);瘢痕组、良性肿瘤组FEV1[(2.0±0.6)%、(1.9±0.6)%]、Vcmax[(2.7±0.5)L、(2.5±0.5)L]大于肉芽肿组[(1.7±0.3)%、(2.3±0.2)L](P0.05),瘢痕组、良性肿瘤组FVC[(2.2±0.2)%、(2.4±0.4)%]小于肉芽肿组(2.7±0.3)%(P0.05)。结论良性气道狭窄治疗中,气管镜介入治疗疗效确切,值得应用。

Effects of interventional bronchoscope treatment on efficacy,the degree of stenosis and shortness of breath score in patients with benign airway stenosis

Objective To explore the effect of interventional bronchoscope treatment on efficacy,the degree of stenosis and the score of shortness of breath of patients with benign airway stenosis.Methods 30 patients with benign airway stenosis admitted to our hospital and Zhongshan Hospital Affiliated to Guangdong Medical University from May 2016 to October 2018 were selected.According to the causes of benign airway stenosis,they were divided into three groups:scar group(n=13),granuloma group(n=12) and benign tumor group(n=5).All patients were treated with interventional bronchoscope.The therapeutic effect,degree of airway stenosis,score of shortness of breath and pulmonary function were compared among the three groups.Results The total effective rates of scar group and benign tumor group were 84.6% and 80.0%,respectively,which were higher than those of granuloma group(75.0%)(P<0.05).The degree of airway stenosis in the scar group[(1.4±0.5)%]was less than that in the granuloma group[(12.2±0.3)%]and benign tumor group[(14.9±0.6)%](P<0.05).There was no significant difference in degree of airway stenosis in the granuloma group and benign tumor group(P>0.05).The shortness of breath score in the scar group was(1.1±0.4) points,which was greater than(0.5±0.1) points in granuloma group and(0.3±0.1) points in the benign tumor group(P<0.05).The forced expiratory volume in 1 second(FEV1) and max vital capacity(Vcmax) in the scar group and benign tumor group was[(2.0±0.6)%,(1.9±0.6)%]and[(2.7±0.5) L,(2.5±0.5) L]respectively,which was greater than[(1.7±0.3)%,(2.3±0.2)L]in the granuloma group(P<0.05).The forced vital capacity(FVC) in the scar group and benign tumor group[(2.2±0.2)%,(2.4±0.4)%]was less than[(2.7±0.3)%]in the granuloma group(P<0.05).Conclusion In the treatment of benign airway stenosis,interventional bronchoscope is effective and worthy of application.