绵阳市汉族中老年人干眼症与非干眼症结膜囊细菌状况对照研究

目的比较绵阳汉族中老年人干眼症与中老年正常人结膜囊细菌状况。方法筛查绵阳市郊区2个聚居点的中老年人群中干眼症80例(160眼),以同一人群中正常人80人(160眼)作为正常对照组进行对比分析,刮取睑结膜囊分泌物培养后进行细菌分离鉴定,比较2组细菌的构成比、细菌种类的复杂性、优势菌种的阳性率等的差异。结果干眼症组结膜囊细菌阳性98眼,阳性率61.3%;对照组结膜囊细菌阳性114眼,阳性率71.3%,2组比较差异无统计学意义(χ2=3.578,P=0.076)。干眼症组培养出111株细菌,86眼为单菌生长(构成比为87.8%),12眼为多菌共存(构成比为12.2%);对照组培养出细菌127株,101眼为单菌生长(构成比为88.6%),13眼为多菌共存(构成比为11.4%),2组比较差异无统计学意义(χ2=0.001,P=0.981)。干眼症组培养出15种细菌,对照组培养出14种细菌。干眼症组革兰阳性菌103眼(构成比为92.8%),正常对照组革兰阳性菌121眼(构成比为95.3%),2组比较差异无统计学意义(χ2=1.454,P=0.483)。2组结膜囊细菌均以棒状杆菌为主,干眼症组棒状杆菌60株(阳性率37.5%,构成比为54.1%);对照组检出棒状杆菌84株(阳性率52.5%,构成比为66.1%),干眼症组较正常对照组阳性率低,差异有统计学意义(χ2=6.679,P=0.010);但2组构成比差异无统计学意义(χ2=3.133,P=0.077);2组表皮葡萄球菌阳性率和构成比比较差异均无统计学意义。结论在自然状况、同一环境下,汉族中老年人干眼症眼与正常眼结膜囊细菌基本为常居菌。其细菌阳性率、细菌共存的多样性、菌种数、革兰分类的构成比以及优势菌株构成比并不受是否为干眼症的影响。

Comparative study on bacterial status in conjunctival sac in middle age and elder of Han nationality with or without dry eye in Mianyang city

Objective To compare the bacteria status in the conjunctival sac between the dry eye and normal eyes of the middle age and elder of Han nationality in Mianyang city.Methods A total of 80 middle age and elders(160 eyes) with dry eye in Mianyang city were examined,and another 80 normal persons(160 eyes) in the same crowd were analyzed as the control group.The secretions of inferior palpebral conjunctivas received to separate and identify the bacteria,the constituent ratio of bacteria,type complexity of bacter...