| 甲状腺相关眼病免疫学发病机理的研究进展 |
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| 引用本文： | 盛海斌,程瑜,蔡昌枰. 甲状腺相关眼病免疫学发病机理的研究进展[J]. 眼科新进展, 2011, 31(10): 991-994 |
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| 作者姓名： | 盛海斌 程瑜 蔡昌枰 |
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| 作者单位： | 1. 上海交通大学医学院附属瑞金医院耳鼻喉科, 上海市,200025
2. 上海交通大学医学院附属医院眼科, 上海市,200025 |
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| 摘 要： | 甲状腺相关眼病目前被认为是一种与Graves病关系密切的器官特异性自身免疫性疾病,其具体发病机制至今仍未明确。已有研究发现:自身抗原、眶内成纤维细胞、免疫细胞、细胞因子及免疫介质等都是该病发病过程中的重要因素。
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| 关 键 词： | 甲状腺相关眼病 发病机理 自身抗原 免疫细胞 眼眶成纤维细胞 |
Research advancement on immunopathogenesis of thyroid-associated ophthalmopathy |
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| SHENG Hai-Bin,CHENG Yu,CAI Chang-Ping. Research advancement on immunopathogenesis of thyroid-associated ophthalmopathy[J]. Recent Advances in Ophthalmology, 2011, 31(10): 991-994 |
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| Authors: | SHENG Hai-Bin CHENG Yu CAI Chang-Ping |
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| Affiliation: | SHENG Hai-Bin,CHENG Yu,CAI Chang-Ping From the Department of Otolarygology,Rujin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China,Department of Ophthalmology,Ruijin Hospital |
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| Abstract: | Thyroid-associated ophthalmopathy is at present regarded as a specific autoimmunal disorder,the pathogenesis of which remains uncertain.Autoantigen,retroorbital fibroblasts,immune cells,cytokines and immune mediators are considered as important pathogenesis factors of thyroid-associated ophthalmopathy. |
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| Keywords: | thyroid-associated ophthalmopathy immunopathogenesis autoantigen immune cell orbital fibroblast |
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