| 鼓室内灌注地塞米松作为重度、极重度突发性聋的补救治疗 |
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| 引用本文： | 黄桂球,傅敏仪,陈美珍. 鼓室内灌注地塞米松作为重度、极重度突发性聋的补救治疗[J]. 医疗保健器具, 2011, 18(10): 1533-1535. DOI: 10.3969/j.issn.1674-4659.2011.10.1533 |
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| 作者姓名： | 黄桂球 傅敏仪 陈美珍 |
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| 作者单位： | 广东省中山市人民医院耳鼻咽喉科,广东,中山,528400 |
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| 摘 要： | 目的鼓室内灌注地塞米松治疗已逐渐应用于突发性耳聋经全身性治疗后无效的患者。本研究对鼓室内灌注地塞米松作为重度、极重度突发性聋的补救治疗的有效性进行评估。方法回顾2007年1月至2009年12月的重度、极重度突聋病例,经全身性治疗后采取鼓室灌注地塞米松的方法治疗14天。采用Sigel标准进行评判,将患者完全或部分恢复听力认作成功治愈。比较重度突聋组和极重度突聋组的治疗效果。结果与极重度突聋组相比,所有重度突聋组患者经治疗后听力均明显提高（P=0.017）。经最初的全身治疗后,重度突聋组的治愈率为36%（9/25）,极重度突聋组的治愈率为18.1%（4/22）（P=0.207）。与之相比,鼓室内应用地塞米松作为补救治疗在重度突聋组的治愈率为37.5%（6/16）,极重度突聋组为5.5%（1/18）（P=0.03）。结论与重度突聋组相比,我们不认为鼓室内灌注地塞米松作为极重度突聋患者的补救治疗有效。建议应事先告知极重度突聋患者此种补救治疗的方法可能疗效欠佳。
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| 关 键 词： | 鼓室内 地塞米松 突发性聋 |
Intratympanic Dexamethasone Perfusion as the Salvage Treatment for Severe and Profound Sudden Hearing Loss |
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| HUANG Guiqiu,FU Minyi,CHEN Meizhen. Intratympanic Dexamethasone Perfusion as the Salvage Treatment for Severe and Profound Sudden Hearing Loss[J]. Medicine Healthcare Apparatus, 2011, 18(10): 1533-1535. DOI: 10.3969/j.issn.1674-4659.2011.10.1533 |
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| Authors: | HUANG Guiqiu FU Minyi CHEN Meizhen |
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| Affiliation: | HUANG Guiqiu,FU Minyi,CHEN Meizhen (Department of Otolaryngology,Head and Neck Surgery,Zhonshan People's Hospital,Zhongshan 528400,China) |
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| Abstract: | Objective Intratympanic dexamethasone perfusion is being increasingly used in the treatment of sudden hearing loss (SHL) after the failure of systemic therapy. This study evaluated the efficacy of administering intratympanic dexamethasone (ITD) as the salvage treatment for severe and profound SHL. Methods We reviewed the medical records of patients who presented with severe and profound SHL from January 2007 to December 2009. ITD was given about 14 days after the initial systemic treatment. Successful recov... |
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| Keywords: | Intratympanic Dexamethasone Sudden hearing loss |
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