Changes in CNTF receptor α expression in rat skeletal muscle during the recovery period after hindlimb suspension |
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Authors: | C. GUILLET,C. HUCHET-CADIOU,H. GASCAN,C. L OTY |
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Affiliation: | C. GUILLET,C. HUCHET-CADIOU,H. GASCAN,C. LÉOTY |
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Abstract: | This study investigated whether modifications in the contractile function of rat muscle after 3 weeks of hindlimb suspension followed by different recovery periods were associated with changes in ciliary neurotrophic factor (CNTF) receptor α. CNTF receptor α was stronger in control extensor digitorum longus (EDL) than soleus. CNTF receptor α was increased in unweighted as compared to control soleus muscle, while no significant changes occurred in EDL muscle. Furthermore, CNTF level was not significantly modified in adult sciatic nerve. |
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