Abstract: | Berberrubine as a natural drug, have varieties of pharmacological activities. Many investigations have been many reported on the synthesis and biological activities of berberrubine.This paper have summarized the anti-cancer,anti-inflammation,anti-nervous system disease,anti-cardiovascular disease,anti-fungus and anti-diabetes of berberrubine.At the same time,the structure modification were also summarized,which provides a reference for its reasonable development and utilization. |