硬化性肺细胞瘤的MSCT特征及18F-FDGPET/CT表现

目的分析肺硬化性肺细胞瘤(pulmonary sclerosing pneumocytoma, PSP)的临床特征、多层螺旋CT(multislice spiral computed tomography, MSCT)和¹⁸F-FDGPET/CT特征,提高PSP术前诊断水平及认识。 方法选择2013年9月至2021年11月我院经手术病理证实后55例PSP患者,分析临床及影像学特征,包括48例CT平扫、33例CT增强、19例¹⁸F-FDGPET/CT全身显像,进一步分析病灶分布、形态、大小、伴随征象、代谢摄取结果,进一步分析了病灶最大直径与最大标准化摄取值(SUV_max)相关性。 结果MSCT显示病灶多为单发(94.5%),边界光滑(89%),呈圆形或椭圆形(85.5%),平均直径25.6 mm。CT主要征象包括贴边血管征(45.5%)、晕征(12.7%)、空气新月征(16.4%)和钙化(41.8%)。增强扫描延迟期趋向均匀持续强化。19例PSP病灶SUV_max,平均值为(2.87±1.20),病灶SUV_max与最大长径呈显著正相关(R＝0.51,P<0.001)。 结论"血管贴边征"、"空气新月征"、"晕征"、"钙化"等特征性PSP患者具有特征性MSCT表现,PSP病灶¹⁸F-FDG PET/CT以中低代谢摄取为主,其大小可能与摄取FDG增加有关,MSCT影像征象、¹⁸F-FDG PET/CT代谢摄取为正确诊断PSP提供了理论依据。

Pulmonary sclerosing pneumocytoma of the lung: MSCT and 18F-FDG PET/CT imaging characteristics

ObjectiveTo describe the detailed clinical, to analyze the detailed clinical features, Imaging Characteristics of PSP under multislice spiral computed tomography (MSCT), and ¹⁸F-fluorodeoxy glucose positron emission tomography (¹⁸F-FDG PET/CT) , in order to improve the preoperative diagnosis. MethodsA total of 55 patients with PSP confirmed by surgical pathology were included, 48 cases received CT plain scan, 33 cases received CT enhanced scan and 19 cases received ¹⁸F-FDGPET/CT imaging. The distribution, morphology, size, clinicoradiological signs and metabolic uptake results of lesions were further analyzed. the relationship between maximum standardized uptake value (SUV_max) and maximum diameter of lesions were observed. ResultsMost patients had a single lesion (94.5%), smooth boundary (89%), and round or oval shape (85.5%), and the mean diameter was 25.6 mm. The mainCT signs included vessel marginal sign (45.5%), halo sign (12.7%), air crescent sign (16.4%) and calcification (41.8%). Delayed phase of Enhanced scanning tends to be continuous and homogeneous enhanced. Besides, The mean maximum standardized uptake value on FDG PET of 19 patients was (2.87±1.20). the maximum standardized uptake value (SUV_max) of 19 patients were significantly positively correlated with the maximum diameter of lesions (R=0.51, P<0.001). ConclusionImaging Characteristics of PSP in MSCT is special, such as vessel marginal sign, halo sign, air crescent sign and calcification. And the ¹⁸F-FDGPET/CT scan revealed hypometabolic FDG uptake in the patients with PSP, which may be related to the increased uptake of FDG. MSCT imaging signs and ¹⁸F-FDGPET/CT metabolic uptake provide a theoretical basis for the correct diagnosis of PSP.