山西省生物安全二级临床实验室生物安全现况调查

目的通过调查问卷方式了解山西省282所生物安全二级（BSL-2）临床实验室生物安全管理现状。 方法自行设计调查问卷，对282所BSL-2临床实验室进行电子问卷调查，内容包括实验室基本情况、安全管理体系文件、组织与营运管理、生物安全设施设备配置、实验室人员培训及管理等。 结果管理体系文件方面，仅有101个实验室办理了菌（毒）种准运证书；组织管理比较完善，95.7%实验室已完成备案管理工作并纳入相应的考评机制；设施设备方面，门禁系统（62.8%）、定向气流（61.7%）、消毒喷雾装置（54.0%）和实验室负压装置（53.2%）配置偏低；人员管理方面，健康评估和体检工作、建档立案不够完善，实验室高级职称人员比例偏低。 结论超过96%实验室的生物安全管理现况较好，要进一步重点完善实验室备案管理、准运证书和目标年度考评等内容的组织管理；优化配置生物安全实验室基础设施设备；要以人为本加强队伍建设。

Biosafety status of BSL-2 clinical investigation laboratory of Shanxi Province

ObjectiveTo understand the current situation of biosafety management of BSL-2 clinical laboratory in Shanxi Province by questionnaire. MethodsA self-designed questionnaire was used to conduct an electronic questionnaire survey in 282 BSL-2 clinical laboratories, including the basic information of the laboratory, organization and operation management, biosafety facilities and equipment configuration, operating procedures and safety inspection, employee management and so on. ResultsIn the management document system, only 101 laboratories have handled the bacterial (virus) species transfer certificate. The organization and management are relatively perfect, and 95.7% of laboratories have completed the filing management and incorporated into the corresponding evaluation mechanism.. In terms of facilities and equipment, the configuration of access control system, biosafety cabinet, directional air flow and negative pressure device is low. In terms of personnel management, the technical, physical examination and evaluation files are not perfect, and the proportion of senior professional titles in the laboratory is low. ConclusionThe biosafety management status of 282 respondents is generally stable and good, and the organization and management of laboratory filing, transportation permit certificate and target evaluation should be strengthened. Biosafety laboratory infrastructure and equipment needs to be optimized. We should put people first and strengthen team building.