膀胱副神经节瘤二例报告及文献复习

目的探讨膀胱副神经节瘤的临床病理特征及其诊治方法。 方法回顾性分析2例膀胱副神经节瘤患者的临床资料，分析该病的临床病理特征、诊断及治疗方法，并对相关文献进行回顾和总结。 结果病例1为无功能性肿瘤，体检发现膀胱占位，CT增强扫描明显强化，肿瘤为单发，行经尿道膀胱肿瘤电切术。病例2为功能性肿瘤，主要临床表现为头痛、心悸、排尿后血压一过性升高，MRI增强结节不均匀强化，肿瘤为单发，术前降压扩容后行腹腔镜膀胱部分切除术，术后症状消失。术后病理诊断均为膀胱副神经节瘤。随访9~12个月，均无复发或转移。 结论膀胱副神经节瘤临床罕见，可分为功能性和非功能性，术前需充分检查及准备，术中预防血压波动引起的高血压危象，经尿道膀胱肿瘤电切术及腹腔镜膀胱部分切除术均效果良好，术后需密切随访。

Paraganglioma of urinary bladder: a report of 2 cases and literature review

ObjectiveTo explore the clinicopathological features, diagnosis and treatment of paraganglioma of urinary bladder (PUB). MethodsThe clinical data, pathological diagnosis and follow-up results of 2 cases with paraganglioma of urinary bladder in our hospital were analyzed retrospectively, and related literatures were also reviewed. ResultsCase 1 was nonfunctional neoplasm without any symptoms. CT scan showed a solitary bladder nodule and was significantly enhanced. The patient underwent transurethral resection of the bladder tumor (TURBT). Case 2 was functional neoplasm with symptoms of headache, palpitation, and paroxysmal hypertension after urination, MRI showed a solitary bladder nodule with heterogeneous enhancement. After sufficient preparation including volume expansion and stability of blood pressure, the patient underwent laparoscopic partial cystectomy and the symptoms disappeared after surgery. There was no tumor recurrence or metastasis through the 9 to 12 months follow-up. ConclusionsPUB is a rare tumor in clinical and can be classified as functional or nonfunctional tumors. Fully preparations should be made to prevent complications such as hypertensive crisis during operation. TURBT and laparoscopic partial cystectomy are effective treatment methods and regular follow-up after surgery is necessary.