国产生物补片与聚丙烯补片在日间腹股沟斜疝Lichtenstein修补术中的疗效对比

目的探讨猪小肠黏膜下层生物补片在腹股沟疝日间手术中的应用价值。 方法回顾分析2019年1月至2020年12月武汉大学中南医院疝病诊疗中心100例接受日间Lichtenstein手术的腹股沟疝患者。根据使用补片的不同分为试验组（SIS补片）和对照组（聚丙烯补片），记录2组患者的临床参数和术后并发症发生情况，对比数据进行统计学分析。 结果2组手术时间，差异无统计学意义（P>0.05）。术后1周，试验组患者术后发热、切口血清肿多于对照组（P<0.05）；而试验组术后切口感染和疼痛发生率均低于对照组（P<0.05）。术后1年，试验组慢性疼痛、异物感发生率均低于对照组（P<0.05）；2组复发率比较，差异无统计学意义（P>0.05）。 结论在开放腹股沟疝手术中，SIS补片术后早期发热及血清肿发生率高于聚丙烯补片，但在早期切口感染及疼痛方面优于聚丙烯补片；在远期慢性疼痛和异物感方面，SIS补片也优于聚丙烯补片，临床应用应遵循个体化原则。

Comparison of the efficacy of domestic biological mesh and polypropylene mesh in daytime Lichtenstein repair of oblique inguinal hernia

ObjectiveTo investigate the application value of porcine small intestinal submucosa biological mesh in day surgery for inguinal hernia. MethodsThe retrospective study enrolled a total of 100 patients with inguinal hernia who underwent Lichtenstein surgery in the ambulatory ward of Zhongnan Hospital of Wuhan University from January 2019 to December 2020. Patients were divided into two groups: the small intestine submucosa mesh (SIS) group and the polypropylene mesh (Control) group. Clinical demographic data, intraoperative data and postoperative complications were collected and analyzed. ResultsIn terms of operative time, there was no statistical significance (P>0.05) between the SIS group and the control group. Analysis of early postoperative outcomes revealed that the number of patients with postoperative fever and seroma significantly increased in the SIS group (P<0.05); the number of patients with postoperative incision infection and postoperative pain significantly decreased in the SIS group (P<0.05). Long-term postoperative outcomes results suggested that the SIS group could significantly improve chronic pain and foreign body sensation compared to the control group (P<0.05). No statistical difference of recurrence rate was found between the SIS group and the control group at 1 year after surgery (P>0.05). ConclusionThe incidence of early postoperative fever and seroma is higher with SIS mesh than with polypropylene mesh, but SIS mesh is superior to polypropylene mesh in terms of early incisional infection and pain. SIS mesh is also superior to polypropylene mesh in terms of distant chronic pain and foreign body sensation, and individualized principles should be followed by clinical application.