Serum lipids in hyper- and hypothyroidism before and after treatment |
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| Authors: | T Friis L R Pedersen |
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| Institution: | 1. Endocrinologic Department, Frederiksberg Hospital, Copenhagen, Denmark;2. Department of Clinical Chemistry, Frederiksberg Hospital, Copenhagen, Denmark;1. Research Unit of Internal Medicine, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland;2. NordLab Oulu, Oulu University Hospital, Oulu, Finland;3. Department of Clinical Chemistry, University of Oulu, Oulu, Finland;1. Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado-Anschutz Medical Campus, Aurora, CO, United States;2. Denver Health and Hospitals, Denver, CO, United States |
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| Abstract: | Total cholesterol (TC), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), triglycerides (TG) and apoprotein A (Apo A) were determined in serum from 21 hyperthyroid patients and 11 hypothyroid patients before and after treatment to euthyroid state. The above-mentioned components were also determined in a reference population. In the hyperthyroid group the concentration of total cholesterol and low density lipoprotein-cholesterol increased significantly upon treatment. High density lipoprotein also increased except for 9 patients also receiving propranolol. The ratio between high density lipoprotein-cholesterol and total cholesterol decreased in the patients receiving propranolol. In the hypothyroid group the values after treatment decreased significantly for cholesterol, high density lipoprotein-cholesterol and low density lipoprotein-cholesterol. The ratio between high density lipoprotein-cholesterol and total cholesterol was unchanged. |
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