产H2S肠道致病性大肠埃希菌0128：K67的发现与研究

目的:对新发现的产 H2S致病性大肠埃希菌进行一系列实验研究,确认该菌在临床实践中的重要意义和流行病学价 值.方法:不同时间、不同标本中分离的产 H2S致病性大肠埃希菌,经形态学、培养特性、生化反应、血清学反应等方 法初步鉴定后,报送国家权威实验室成都生物制品研究所鉴定并命名.结果:在腹泻、食物中毒病人标本、水源水中分离的 4株产 H2S致病性大肠埃希菌,经全面鉴定后,均为 EPEC O128: k67.结论:产 H2S致病性大肠埃希菌的发现 使致病大肠埃希菌家族增加了新的成员,为微生物学研究拓展了新的领域;该菌与大肠埃希菌有密切的亲缘关系, 是变异的致泻性大肠埃希菌;因其具有较强的致病性,故应引起有关部门的高度重视并采取相应的防治对策防止该 菌造成新的腹泻病的传播和蔓延.

Discovery and study on pathogenic E .coli of producing H2S

Objective We confir med that pathogenic E .coli of producing H 2 S has important signification and epidemiological value in clinical practice through a series of experime ntal study on them .Methods Various serotypes of pathogenic E .coli of producing H 2 S were separated from different time s and samples.After they were pulimi-narily identified through morpholo gy,cultural characteristic ,bioch emisty reaction ,serology etc micro biological i-dentification,they were sent to Che ngdu Biological Identfication Institute which is one of national authoritative l aboratories in order to be finally i dentified and named.Results Four strains o f pathogenic E.coli of producing H 2 S were separated from diarrhea,food p oisoning patients and water sources, which were confirmed that they were EPEC O128:K67.Conclusion The discover y of pathogenic E .coli o f producing H 2 S led to increase E .coli members and opened up new field of micro-biolog ical study.The baeteria were variati ons of pathogenic E coli,which had close consanguinity with pathogenic E .co li.So they had very strong pathogeni city We should think highly of them an d take some measures to prevent new dia rrhea propagative and spread.