Considering the senses in the diagnosis and management of dementia |
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Authors: | Sophie Behrman Leonidas ChouliarasKlaus P. Ebmeier |
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Affiliation: | Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK |
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Abstract: | Associations between dementia and impairments in hearing, vision, olfaction and (to a lesser degree) taste have been identified. Hearing impairment has been shown to precede cognitive decline, but it is not clear if the hearing loss is an early marker of dementia or a modifiable risk factor. Olfactory impairment is seen in many neurodegenerative conditions, but it has been shown that those with dementia have particular difficulties with the recognition and identification of odours rather than the detection, suggesting a link to impairment of higher cognitive function. Olfactory impairment has been shown to be predictive of conversion from mild cognitive impairment to Alzheimer's disease with 85.2% sensitivity. |
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Keywords: | NICE, National Institute for Health and Care Excellence BPSD, behavioral and psychological symptoms of dementia MMSE, mini mental state examination AD, Alzheimer's disease PD, Parkinson's disease UPSIT, University of Pennsylvania smell identification test MCI, mild cognitive impairment OR, odds ratio DLB, dementia with Lewy bodies AMD, age-related macular degeneration CBS, Charles-Bonnet syndrome ADL(s), activities of daily living CGI, Clinical Global Impression of Change |
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