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Considering the senses in the diagnosis and management of dementia
Authors:Sophie Behrman  Leonidas ChouliarasKlaus P. Ebmeier
Affiliation:Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK
Abstract:Associations between dementia and impairments in hearing, vision, olfaction and (to a lesser degree) taste have been identified. Hearing impairment has been shown to precede cognitive decline, but it is not clear if the hearing loss is an early marker of dementia or a modifiable risk factor. Olfactory impairment is seen in many neurodegenerative conditions, but it has been shown that those with dementia have particular difficulties with the recognition and identification of odours rather than the detection, suggesting a link to impairment of higher cognitive function. Olfactory impairment has been shown to be predictive of conversion from mild cognitive impairment to Alzheimer's disease with 85.2% sensitivity.
Keywords:NICE, National Institute for Health and Care Excellence   BPSD, behavioral and psychological symptoms of dementia   MMSE, mini mental state examination   AD, Alzheimer's disease   PD, Parkinson's disease   UPSIT, University of Pennsylvania smell identification test   MCI, mild cognitive impairment   OR, odds ratio   DLB, dementia with Lewy bodies   AMD, age-related macular degeneration   CBS, Charles-Bonnet syndrome   ADL(s), activities of daily living   CGI, Clinical Global Impression of Change
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