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Nanomolar levels of PAHs in extracts from urban air induce MAPK signaling in HepG2 cells |
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| Authors: | I.W.H. Jarvis C. Bergvall D.A. Morales F. Kummrow G.A. Umbuzeiro R. Westerholm U. Stenius K. Dreij |
| Affiliation: | 1. Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77 Stockholm, Sweden;2. Department of Analytical Chemistry, Stockholm University, Svante Arrhenius väg 16, SE-106 91 Stockholm, Sweden;3. Faculty of Technology, State University of Campinas (UNICAMP), Limeira, São Paulo 13484-332, Brazil;4. Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo (UNIFESP), Diadema, São Paulo 09972-270, Brazil |
| Abstract: | |
| Keywords: | AP-1, activator protein 1 BP, benzo[a]pyrene ERK, extracellular regulated kinase JNK, c-Jun N-terminal kinase MAPK, mitogen-activated protein kinase MEK4, MAPK kinase 4 PAH, polycyclic aromatic hydrocarbon PM, particulate matter TEF, toxic equivalency factor TNF, tumor necrosis factor |
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