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我院2011-2013年抗肿瘤药使用分析
引用本文:周虹,;蔡文杰,;林志强.我院2011-2013年抗肿瘤药使用分析[J].中国药房,2014(46):4325-4328.
作者姓名:周虹  ;蔡文杰  ;林志强
作者单位:[1]福建医科大学附属泉州第一医院药剂科,福建泉州362000; [2]福建医科大学附属泉州第一医院放疗科,福建泉州362000
摘    要:目的:了解我院抗肿瘤药的使用情况及趋势。方法:结合我院肿瘤分类构成情况,采用用药频度(DDDs)和金额排序法对2011-2013年我院抗肿瘤药的应用情况进行分析。结果:各年度肺癌、乳腺癌、食管癌构成排序均居前3位。植物来源的抗肿瘤药及其衍生物、抗代谢药和其他抗肿瘤药各年度销售金额均居前3位,约占总销售金额的80%;多西他赛、紫杉醇销售金额连续3年均居前3位;各年度DDDs排序前3位均为卡培他滨、替吉奥、氟尿嘧啶。结论:我院抗肿瘤用药倾向于抗代谢药,而紫杉烷类、铂类应用也较多,但分子靶向药品种少、市场份额小。

关 键 词:闽南地区  抗肿瘤药  销售金额  用药频度  日均费用

Analysis of the Utilization of Antitumor Drugs in Our Hospital from 2011 to 2013
Institution:ZHOU Hong, CAI Wen-jie, LIN Zhi-qiang ( 1. Dept. of Pharmacy, Quanzhou First Hospital Affiliated to Fujian Medical University, Fujian Quanzhou 362000, China; 2. Dept. of Radiation Oncology, Quanzhou First Hospital Affiliated to Fujian Medical University, Fujian Quanzhou 362000, China)
Abstract:OBJECTIVE: To investigate the application and trend of antitumor drugs in our hospital. METHODS: Combined with the composition of tumor, the utilization of antitumor drugs in our hospital from 2011 to 2013 was analyzed statistically in terms of consumption sum and DDDs. RESULTS: Top 3 tumors in the list of composition ranking were lung cancer, breast cancer and esophageal cancer for 3 consecutive years. Top 3 drugs varieties in the list of consumption sum were antitumor drug and its de- rivative, antimetabolites and other antitumor drug, which accounted for nearly 80% of total consumption sum. Docetaxel and pacli- taxel occupied the first 3 places in the list of consumption sum in 3 years. Top 3 drugs in the list of DDDs were capecitabine, S-1 and fluorouracil. CONCLUSIONS: Medication regimen tends to antimetabolites, while platinum and taxanes are used frequently. But the targeted drug is poor in variety and market share.
Keywords:Southern Fujian  Antitumor drugs  Consumption sum  DDDs  DDC
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