| 蒙药复方协日嘎四味汤散的化学成分研究 |
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| 引用本文： | 高建华,杨婷,董玉.蒙药复方协日嘎四味汤散的化学成分研究[J].中国药房,2014(47):4470-4472. |
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| 作者姓名： | 高建华 杨婷 董玉 |
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| 作者单位： | 内蒙古医科大学药学院,呼和浩特010059 |
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| 基金项目： | 内蒙古自治区自然科学基金资助项目（No.2013JQ03）;内蒙古自治区科技计划项目（No.20120411） |
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| 摘 要： | 目的:研究蒙药复方协日嘎四味汤散的化学成分。方法:采用硅胶柱色谱法和柱色谱法分离纯化复方协日嘎四味汤散的提取物,根据其理化性质并运用波谱技术鉴定化合物结构。结果:从复方协日嘎四味汤散中分离得到11个化合物,经鉴定为黄柏酮(1)、黄柏内酯(2)、十六烷酸(3)、去甲氧基姜黄素(4)、姜黄素(5)、小檗碱(6)、双去甲氧基姜黄素(7)、姜黄醇(8)、香草酸(9)、汉黄芩素(10)、京尼平苷龙胆二糖苷(11)。结论:鉴定的11个化合物均为首次从该复方中分离得到。本试验结果可为复方协日嘎四味汤散的药效物质基础研究提供依据。
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| 关 键 词： | 复方协日嘎四味汤散 化学成分 分离 结构鉴定 |
Study on Chemical Component of Mongolian Medicine Compound Xieriga Siwei Soup Powder |
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| GAO Jian-hua,YANG Ting,DONG Yu.Study on Chemical Component of Mongolian Medicine Compound Xieriga Siwei Soup Powder[J].China Pharmacy,2014(47):4470-4472. |
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| Authors: | GAO Jian-hua YANG Ting DONG Yu |
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| Institution: | (College of Pharmacy, Inner Mongolia Medical University, Hohhot 010059, China) |
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| Abstract: | OBJECTIVE： To study the chemical components of Mongolian medicine Compound xieriga siwei soup powder. METHODS： The extracts were isolated and purified from Compound xieriga siwei soup powder by silica gel column chromatogra- phy and column chromatography. The structures of compounds were identified by spectroscopy according to physicochemical proper- ties. RESULTS： 11 compounds were isolated from effective fraction of Mongolian medicine Compound xieriga siwei soup powder as obacunone （ 1 ）, obaculactone （2）, palmitic acid （3）, demethoxycurcumin （4）, eurcumin （5）, berberine hydrochloride （6）, bisdemethoxy curcumin （7）, curcumenol （8）, vanillic acid （9）, wogonin （10） and genipin gentiobioside （11）. CONCLUSIONS： The 11 compounds are isolated from the compound for the first time. This study can provide reference for fundamental research of effective substance from Compound xieriga siwei soup powder. |
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| Keywords: | Compund xieriga siwei soup powder Chemical component Isolation Structure identification |
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