我院2011-2013年临床药师参与300例患儿应用抗菌药物会诊分析

目的:了解临床药师参与会诊的落实情况和结果,为临床药师更好地参与临床工作提供依据。方法:对2011-2013年我院临床药师参与300例16岁以下患儿临床感染疾病的会诊情况,包括申请会诊目的及内容、会诊模式、肝肾功能、会诊科室、菌群分布、会诊建议是否采纳、治疗转归、使用前5位的抗菌药物、非肝肾受损不良反应等进行统计分析。结果:申请会诊科室中以儿科普通病区最多(45.33%,136/300),其次为儿科重症病区(PICU);申请会诊目的以指导选择、调整抗菌药物为主(87.67%,263/300);会诊建议被全部采纳的有253例(占84.30%),部分采纳的有28例(占9.33%),未采纳的有19例(占6.33%)。意见采纳后再行治疗,痊愈50例(占16.66%),好转127例(占42.33%),效果不明显71例(占23.66%),其他33例(占11.00%)。结论:临床药师会诊已经成为临床治疗工作的一部分,在感染疾病治疗中起到了积极作用。

Analysis of Clinical Pharmacists Participating in 300 Cases of Children Antibacterial Drugs Consultation in Our Hospital during 2011--2013

OBJECTIVE： To probe into the practice and results of clinical pharmacists participating in consultations so as to provide reference for clinical pharmacists participating in clinical practice in the future. METHODS ： The pratice of clinical pharma- cists participating in 300 cases of clinical consultation for the children under 16 years-old with infection disease during 2011- 2013 were analyzed statistically in following aspects： purpose and contents for consultation, consultation mode, hepatorenal function, the departments of consultation, pathogens distribution, the acceptance of consultative suggestions, treatment outcome, top 5 antbi- bacterial drugs, non-hepatorenal ADR, etc. RESULTS： Most consultation occurred in wards of general pediatrics （45.33 %, 136/ 300）, followed by pediatric intensive care unit （PICU）. The main purpose was to adjust or guide the use of antibacterial drugs （87.67%, 263/300）. A total of 253 cases of consultation comments （84.30%） were adopted completely, 28 cases （9.33%） were adopted partly, and 19 cases （6.33 % ） were refused. After the acceptation of consultations, 50 patients were cured （ 16.66 % ）, 127 were improved （42.33%）, 71 were invalid （23.66%）, and the others were 33 cases （11.00%）. CONCLUSIONS： The participa- tion of clinical pharmacists in consultation has became a part of medical treatment, and plays an important active role in the treat- ment of infection disease.